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The Real Deal About Taking Tylenol When You're Expecting

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What Makes Tylenol Different From Other Pain Relievers: Acetaminophen — also known as paracetamol and sold under the brand name Tylenol — is considered the only safe over-the-counter option for pain or fever for pregnant people.  Unlike aspirin and ibuprofen, which doctors tell pregnant women to avoid, Tylenol works differently in your body. It treats pain and fever without affecting blood flow to your baby or causing problems with your pregnancy.